The Claflin University Molecular Science Research Center has been designated a Research Core Facility Core Research Facility for the state by the South Carolina Research Authority because of specialized analytical equipment in the Molecular Science Research Center. Claflin has the second largest NMR in the state of South Carolina, 700 MHz Bruker NMR. 

Claflin's NMR facility, in addition to its 700 MHz NMR, also has an automated nuclear magnetic resonance (NMR) sample changer to do NMR-based metabolomics research. The field of metabolomics focuses on changes to the small molecules that make up metabolism upon some stressful event or condition. NMR serves as an excellent detector of these small compounds; and statistical analysis is applied to many NMR sample replicates to increase the robustness of the metabolomics technique. Although a predominately undergraduate university and HBCU (Historically Black Colleges and Universities), Claflin University has the third highest field NMR laboratory in the state of South Carolina, just behind the Medical University of South Carolina (MUSC) and the Hollings Marine Laboratory (HML).